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Whose View of Life? – Embryos, Cloning and Stem Cells whose view of life – embryos cloning and stem cells
Whose View of Life? – Embryos, Cloning and Stem Cells
1827 RUR
Derivation of embryonic stem cells in buffalo whose view of life – embryos cloning and stem cells
This monograph will have practical use to those who are interested to establish embryonic stem cells laboratory. Embryonic stem cells are one of the emerging areas in reproductive biotechnologies in buffalo, which could have enormous agricultural and biomedical applications. Besides its immense potential in humans, the stem cell technology has proved to be a boon for farm animals since promising results have been obtained in the fields of gene targeting, cloning, transgenesis, chimera formation and differentiation into germ cells (sperm and oocytes). This book mainly deals with the isolation, culture, characterization and differentiation of embryonic stem cells generated from in vitro fertilized embryos in buffalo and grown on different feeder cells. It will also give the overview of preparation of feeder cells, cryopreservation, in vitro fertilization and parthenogenetic activation.
5576 RUR
Embryonic Stem Cell-like Cells in Goat (Capra hircus) whose view of life – embryos cloning and stem cells
The objective of the present experiment was production of goat embryos either by parthenogenetic activation or by in vitro fertilization and derivation of embryonic stem (ES) cell-like cells. Firstly, the effects of different activation methods, culture systems and culture media on in vitro development of zona-free and with-zona parthenogenetic embryos were investigated. Secondly, effect of cysteamine supplementation in the in vitro maturation (IVM) or culture (IVC) media, or a combination of both in terms of blastocyst production by in vitro fertilization was investigated. Finally, different methods of isolation of ES cell-like cells from in vitro produced embryos were compared and effects of Leukaemia Inhibitory Factor (LIF) and different types of feeder layers on growth of ES cell-like cells were investigated. The undifferentiated ES cell-like cells showed stem cell like morphological features, normal karyotype, expressed stem cell specific surface and intracellular markers and maintained undifferentiated state for long periods in culture. Mechanical isolation of ICMs from hatched blastocysts was found to be the best method to establish goat ES cell-like cells.
4468 RUR
Stem cells in dentistry - dreams to reality whose view of life – embryos cloning and stem cells
Stem cell biology has become an important field for the understanding of tissue regeneration and implementation of regenerative medicine. The discovery of dental stem cells and recent advances in cellular and molecular biology have led to the development of novel therapeutic strategies that aim at the regeneration of oral tissues that were injured by diseases or trauma. Medicine and dentistry are on the cusp of a new treatment modality. Recent exciting new discoveries place dentists at the fore front for helping their patients from potentially life-saving therapies derived from patient’s own stem cells.
3393 RUR
Microchimeric Fetal Stem cells in Pregnancy whose view of life – embryos cloning and stem cells
Stem cells are one of the keys to life,they potentially nourish,heal and protect us. Stem cells are truly remarkable. They bridge the gap between our origin and what we become. They supply the cells that construct our adult bodies and, as we age, replenish damaged and diseased tissues. A true stem cell is a primitive cell capable of unlimited cell cycles with the capacity to cease being a stem cell and become one of a wide variety of specialized cells that can no longer divide Fetal stem cells cross into maternal blood during pregnancy and thus represent a potential non- invasive source of foetal genetic material for prenatal diagnosis.
4631 RUR
Stem cells whose view of life – embryos cloning and stem cells

Stem cells

4631 RUR
Stem cells whose view of life – embryos cloning and stem cells
Cell is the structural and functional unit of life. A living cell is a true representative of life with its own organisation and specialised functions. Scientists have been interested in cell biology since the advent of microscopes in 18th century. Stem cells are defined as clonogenic, unspecialised cells capable of both self renewal for long periods and multilineage differentiation contributing to regenerate specific tissues. They can theoretically divide without limit to replenish other cells as long as the person is still alive. Research on stem cells and their application to treat various diseases is still at a preliminary stage. However, results from animal models are very promising and many researchers believe that it is only a matter of time before the same results can be achieved with human stem cell.
4631 RUR
Mesenchymal Stem Cells Therapy for treatment of Liver Cirrhosis whose view of life – embryos cloning and stem cells
Hepatic cirrhosis is the end stage of chronic liver disease, the majority of patients with cirrhosis die from life threatening complications. Recently, Mesenchymal stem cells show ability to differentiate into hepatocytes, stimulate the regeneration of endogenous parenchymal cells and enhance fibrous matrix degradation. Thus, this study aimed to evaluate the possible therapeutic effect of mesenchymal stem cells in thioacetamide (TAA) induced liver cirrhosis in rats. Animal model of liver cirrhosis was induced by intraperitoneal injection of thioacetamide.Ten albino rats weighting 100-120 g were used for isolation of bone marrow derived mesenchymal stem cells(BM-MSCs) and thirty-five healthy albino rats weighting 150-200 g were divided into three groups; control, cirrhotic and treated groups. After the experimental period, blood samples and liver tissue were collected for determination of biochemical parameters. Results showed that administration of BM-MSCs improved liver functions and reduced hydroxyproline content.
6201 RUR
Reprogramming of human Fibroblast into Induced Pluripotent Stem Cells whose view of life – embryos cloning and stem cells
Human Embryonic stem cells (hESCs) represent a pluripotent cell population derived from the inner cell mass of the blastocyst stage of the developing embryo. Ethical concerns have been raised regarding the derivation process, as the procedure ultimately results in the destruction of the embryos. Recently, alternative approach has been devised that encompasses reprogramming of terminally differentiated cells into a hESC-like state. This process relies on the over-expression of four pluripotency-associated factors, and successfully reprogrammed cells are termed induced pluripotent stem cells. These cells hold great promise for the use in future cell-based therapeutics such as evaluating drug induced toxicity and developing personalized medicines. However, the intricacies of the reprogramming mechanism are not fully understood, mostly due to the random nature of the expression of the four transcription factors. In this study, a novel molecular switch, known as Rheostat system, was utilized in conjunction with the doxycycline system to regulate the expression of the transcription factors in a precise temporal manner and elucidate underlying mechanisms of the reprogramming process.
4468 RUR
Stem Cells : Hope and Scope in the field of Dentistry whose view of life – embryos cloning and stem cells
It is believed that a damaged tooth cannot self repair by itself. Current dentistry resolves these problems using autologous tissue grafts or metallic implants but these treatment options have some limitations.Therefore research has led to a conclusion that stem cell bio engineered tooth is a promising way of single tooth restorations. Hence this current text offers a contemporary guide of hope and scope of stem cell in the field of dentistry.
4631 RUR
Stem Cells: An update In Dentistry whose view of life – embryos cloning and stem cells
In the face of extraordinary advances in the prevention, diagnosis, and treatment of human diseases, the inability of most tissues and organs, to repair and regenerate after damage is a problem that needs to be solved. Stem cell research is being pursued in the hope of achieving major medical breakthroughs.In maxillofacial region the Regeneration & Repair of damaged periodontal tissue, bone, pulp, and dentin are problems that the dentist faces today. Stem cells have potential to regenerate dentin, periodontal ligament, cementum and can be used for bone defect therapy. The proper utilization of stem cells can full fill the quest to live a long and healthy life which is as old as the appearance of the first cell on earth. So this book basically aims at reviewing the stem cells types, sources, clinical implications both in medical and dental field and along with their roll in tissue engineering.
5576 RUR
Dictionary of Stem Cells, Regenerative Medicine, and Translational Medicine whose view of life – embryos cloning and stem cells
Stem cells, regenerative medicine, and translational medicine, are all areas of burgeoning basic research and clinical application. This dictionary includes the fundamental terminology of each of these areas, the major discoveries and significant scientists that comprise the history and current development of the field, as well as a number of concepts. The vocabulary is presented within the broader lexicon of developmental biology and embryology, which provides context for these three fields. Topics covered range from stem cells (embryonic, adult, and iPSCs) to teratology. The inclusion of extensive cross-referencing of the terms will enable readers to broaden their understanding of them. The Dictionary of Stem Cells, Regenerative Medicine, and Translational Medicine will provide both the basic background terminology needed by pre-health professions/biology major undergraduate students and early-stage graduate students, as well as being a valuable reference for university professors, researchers and peers in related disciplines.
13068 RUR
Stem cells microenvironment and its effects on leukemia treatment whose view of life – embryos cloning and stem cells
Acute lymphoblastic leukemia is one of the most common forms of leukemia that affects children. Although a remarkable achievement in cure rate is seen, still the percent of children is facing the risk of death due to the resistance to drug or toxic side effects of treatment. Glucocorticoids such as dexamethasone are regularly used in the treatment because of its pro-apoptotic effects. Recent studies highlighted the role of bone marrow stem cells in developing resistance and failure of the treatment and subsequently death of the patient. In this book, we demonstrated the importance of considering how combined drug treatment is different from individual drug treatment and how the bone marrow stem cells can affects drug resistance. In conclusion, our findings can increase the understands of the biological and molecular aspects of the differences between the sensitive and resistant cells in acute lymphoblastic leukemia and the effect of the stem cell niche on the therapy which can contribute to more efficient, less toxic therapy.
3821 RUR